Feasibility of rapid quantitation of stratum corneum lipid content by Fourier transform infrared spectrometry
نویسندگان
چکیده
منابع مشابه
Fourier transform infrared spectrometry.
The theory and instrumentation for Fourier transform infrared spectrometry are discussed. These instruments measure infrared spectra of the same quality as spectra measured on grating spectrometers in about one thousandth of the time. Their sensitivity advantage for spectra measured in equal times is between a factor of 10 and 100. Commercial spectrometers are now available from nine vendors in...
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A new Fourier Transform-Infra Red (FT-IR) spectrometric method was developed for assaying hydrochlorothiazide (HCT) and enalapril maleate (ENM) in binary solid pharmaceutical formulations. Multivariate Partial Least Squares (PLS) method was used for calibration of derivative spectral data. Acetonitrile was used as solvent due to its spectral tran...
متن کاملRapid Scanning Fourier Transform Spectrometry
Rapid scanning serves to mitigate the problems of scintillation and dynamic range for Fourier spectrometry, as well as to simplify the measurement procedures. Rapid scanning means scanning at a rate such that the interferometric fringes act as their own chopper. It also means scanning at a rate such that the fringe frequencies exceed the scintillation frequencies, thereby avoiding confusion bet...
متن کاملSimulation studies of stratum corneum lipid mixtures.
We present atomistic molecular dynamics results for fully hydrated bilayers composed of ceramide NS-24:0, free fatty acid 24:0 and cholesterol, to address the effect of the different components in the stratum corneum (the outermost layer of skin) lipid matrix on its structural properties. Bilayers containing ceramide molecules show higher in-plane density and hence lower rate of passive transpo...
متن کاملThe physics of stratum corneum lipid membranes.
The stratum corneum (SC), the outermost layer of skin, comprises rigid corneocytes (keratin-filled dead cells) in a specialized lipid matrix. The continuous lipid matrix provides the main barrier against uncontrolled water loss and invasion of external pathogens. Unlike all other biological lipid membranes (such as intracellular organelles and plasma membranes), molecules in the SC lipid matrix...
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ژورنال
عنوان ژورنال: Spectroscopy
سال: 2004
ISSN: 0712-4813,1875-922X
DOI: 10.1155/2004/401015